Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes.

@article{Wilinska2010SimulationET,
  title={Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes.},
  author={Malgorzata E. Wilinska and Ludovic J. Chassin and Carlo L Acerini and Janet M. Allen and David B Dunger and Roman Hovorka},
  journal={Journal of diabetes science and technology},
  year={2010},
  volume={4 1},
  pages={132-44}
}
BACKGROUND Closed-loop insulin delivery systems linking subcutaneous insulin infusion to real-time continuous glucose monitoring need to be evaluated in humans, but progress can be accelerated with the use of in silico testing. We present a simulation environment designed to support the development and testing of closed-loop insulin delivery systems in type 1 diabetes mellitus (T1DM). METHODS The principal components of the simulation environment include a mathematical model of glucose… CONTINUE READING

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