Simulation and probabilistic failure prediction of grafts for aortic aneurysm

  title={Simulation and probabilistic failure prediction of grafts for aortic aneurysm},
  author={Ron Layman and Samy Missoum and Jonathan P. Vande Geest},
  journal={Engineering Computations},
Purpose – The use of stent‐grafts to canalize aortic blood flow for patients with aortic aneurysms is subject to serious failure mechanisms such as a leak between the stent‐graft and the aorta (Type I endoleak). The purpose of this paper is to describe a novel computational approach to understand the influence of relevant variables on the occurrence of stent‐graft failure and quantify the probability of failure for aneurysm patients.Design/methodology/approach – A parameterized fluid‐structure… 

Patient-specific numerical simulation of stent-graft deployment: Validation on three clinical cases.

Numerical Modeling of Blood Flow in a Healthy Aorta and Aorta with Stent

The obtained results show a nearly similar tendency of variation for both models, which justifies the effectiveness of the type of stent chosen and its effect on the improvement of the blood flow.

The Impact of a realistic complete Stenting Procedure on the Migration Behaviour: a Numerical Analysis

The simulation results show that the realistic deployment method did indeed influence the mechanical behaviour, positioning, and eventually the functioning of the stent-graft when compared with the traditional deployment methods.

Polymeric Endo-Aortic Paving (PEAP): Initial Development of a Novel Treatment for Abdominal Aortic Aneurysms

It is hypothesized that PEAP will overcome many of the limitations associated with EVAR by providing a minimally invasive treatment which can be used on patients with complicated AAA geometries and reducing incidence of migration and endoleak.

Deployment of stent grafts in curved aneurysmal arteries: toward a predictive numerical tool

Finite element analysis was carried out to simulate the expansion of five marketed stent graft iliac limbs and to evaluate quantitatively their mechanical performances.

Wall Stress Reduction in Abdominal Aortic Aneurysms as a Result of Polymeric Endoaortic Paving

It is shown that wall stress reduction increases with increasing PEAP thickness and PCL content in the blend ratio, and it is proposed that PEAP may provide an improved treatment alternative for AAA, since many of the limitations of stent-grafts have the potential to be solved using this approach.

Modelling and simulation of the expansion of a shape memory polymer stent

This is the first time that the expansion performance of a SMP stent has been analyzed both qualitatively and quantitatively through modelling and simulation.

Probabilistic predictive modelling of carbon nanocomposites for medical implants design.

  • M. ChuaC. Chui
  • Engineering
    Journal of the mechanical behavior of biomedical materials
  • 2015

3D fluid-structure interaction (FSI) simulation of new type vortex generators in smooth wavy fin-and-elliptical tube heat exchanger

Purpose The purpose of this paper is to investigate the numerical fluid-structure interaction (FSI) framework for the simulations of mechanical behavior of new vortex generators (VGs) in

Reliability Assessment using

This article presents a new probability of failure measure based on the notion of probabilistic support vector machines (PSVMs). A PSVM allows one to quantify the probability of having an error in



Blood flow and structure interactions in a stented abdominal aortic aneurysm model.

Computational analysis of type II endoleaks in a stented abdominal aortic aneurysm model.

A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysms.

Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models

The results suggest that fully coupled FSI simulation, which requires considerable computational power to run, adds little to rupture risk prediction, and justifies the use of SS models in previous studies.

Analysis of biomechanical factors affecting stent-graft migration in an abdominal aortic aneurysm model.

A patient-specific computational model of fluid-structure interaction in abdominal aortic aneurysms.

Fluid-structure interaction in abdominal aortic aneurysms: effects of asymmetry and wall thickness

Both wall thickness and geometry asymmetry affect the stress exhibited by a virtual AAA, and the results suggest that an asymmetric AAA with regional variations in wall thickness would be exposed to higher mechanical stresses and an increased risk of rupture than a more fusiform AAA with uniform wall thickness.

Computational analysis of biomechanical contributors to possible endovascular graft failure

After EVG insertion for the given model, the peak AAA sac-pressure was reduced, and hence the maximum von Mises wall stress and wall deformation dropped by factors of 20 and 10, respectively, and an EVG can significantly reduce sac pressure, mechanical stress, pulsatile wall motion, and the maximum diameter in AAAs and hence prevent AAA rupture effectively.

Effects of major endoleaks on a stented abdominal aortic aneurysm.

Interestingly enough, the net downward force acting on the implant is significantly reduced; thus, in the presence of endoleaks, the risk of stent-graft migration may be mitigated, and both proximaltype I-a and distal type I-b endoleak may cause cavity pressures close to a patient's systemic pressure; however, with reduced pulsatility.