Simulation Analysis of Lateral Propagation Mechanism of EGF Signaling on Cell Surface

  • Takashi Naka
  • Published 2009 in
    2009 International Conference on Computational…


Newly developed microscopic technology has recently made it possible to directly visualize lateral signaling events in a single cell in which the local stimulation of EGFR with EGF yields global phosphorylation of EGFR on the whole cell membrane. The putative feedback mechanism of receptor phosphorylation by ligand-free phosphorylated receptors has been… (More)
DOI: 10.1109/ICCSA.2009.40


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