Simulating tumor growth in confined heterogeneous environments.

  title={Simulating tumor growth in confined heterogeneous environments.},
  author={Jana L. Gevertz and George T. Gillies and Salvatore Torquato},
  journal={Physical biology},
  volume={5 3},
The holy grail of computational tumor modeling is to develop a simulation tool that can be utilized in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies. In order to develop such a predictive model, one must account for many of the complex processes involved in tumor growth. One interaction that has not been incorporated into computational models of neoplastic progression is the impact that organ-imposed physical confinement and heterogeneity… CONTINUE READING
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