Simulating short- and long-term evolutionary dynamics on rugged landscapes

  title={Simulating short- and long-term evolutionary dynamics on rugged landscapes},
  author={Leonardo Trujillo and Paul Banse and Guillaume Beslon},
We propose a minimal model to simulate long waiting times followed by evolutionary bursts on rugged landscapes. It combines point and inversions-like mutations as sources of genetic variation. The inversions are intended to simulate one of the main chromosomal rearrangements. Using the well- known family of NK fitness landscapes, we simulate random adaptive walks, i.e. successive mutational events con- strained to incremental fitness selection. We report the emer-gence of different time scales: a… 

Figures from this paper



Small world effects in evolution.

  • F. BagnoliM. Bezzi
  • Biology
    Physical review. E, Statistical, nonlinear, and soft matter physics
  • 2001
It is shown that a small-world effect is present: even a small fraction of quenched long-range jumps makes the results indistinguishable from those obtained by assuming all mutations equiprobable.

Key issues review: evolution on rugged adaptive landscapes

The concept of adaptive landscapes is introduced, the major theoretical studies of evolution on rugged landscapes are reviewed, and recent mathematical and statistical analyses motivated by empirical adaptive landscapes are discussed.

The million-year wait for macroevolutionary bursts

It is suggested that these rare bursts of phenotypic change reflect permanent changes in adaptive zones, whereas the short-term fluctuations represent local variations in niche optima due to restricted environmental variation within a stable adaptive zone.

Genetic Algorithms on NK-Landscapes: Effects of Selection, Drift, Mutation, and Recombination

This work takes a model of generational parallel varying mutation GA (GASRM) and switch on and off its major components to emphasize each of the four processes mentioned above and concludes that NK-Landscapes are useful for testing the GA's overall behavior and performance and also for testing each one of the major processes involved in a GA.

Towards a general theory of adaptive walks on rugged landscapes.

Impact of epistasis and pleiotropy on evolutionary adaptation

It is implied that the synergism between loci that interact epistatically is crucial for evolving genetic modules with high fitness, while too much ruggedness stalls the adaptive process.

Punctuated equilibria: the tempo and mode of evolution reconsidered

It is argued that virtually none of the examples brought forward to refute the model of punctuated equilibria can stand as support for phyletic gradualism; many are so weak and ambiguous that they only reflect the persistent bias for gradualism still deeply embedded in paleontological thought.

Lévy flights in neutral fitness landscapes

Origins of Order: self-organization and selection in evolution

The structure of rugged fitness landscapes and the structure of adaptive landscapes underlying protein evolution, and the architecture of genetic regulatory circuits and its evolution.

The NK model of rugged fitness landscapes and its application to maturation of the immune response.