Corpus ID: 88516944

Simulating realistically complex comparative effectiveness studies with time-varying covariates and right-censored outcomes

  title={Simulating realistically complex comparative effectiveness studies with time-varying covariates and right-censored outcomes},
  author={Maria E. Montez-Rath and Kristopher I. Kapphahn and Maya B. Mathur and Natasha Purington and Vilija R. Joyce and Manisha Desai},
  journal={arXiv: Applications},
Simulation studies are useful for evaluating and developing statistical methods for the analyses of complex problems. Performance of methods may be affected by multiple complexities present in real scenarios. Generating sufficiently realistic data for this purpose, however, can be challenging. Our study of the comparative effectiveness of HIV protocols on the risk of cardiovascular disease -- involving the longitudinal assessment of HIV patients -- is such an example. The correlation structure… 
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