Simulating PDGF-Driven Glioma Growth and Invasion in an Anatomically Accurate Brain Domain.

Abstract

Gliomas are the most common of all primary brain tumors. They are characterized by their diffuse infiltration of the brain tissue and are uniformly fatal, with glioblastoma being the most aggressive form of the disease. In recent years, the over-expression of platelet-derived growth factor (PDGF) has been shown to produce tumors in experimental rodent… (More)
DOI: 10.1007/s11538-017-0312-3

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