Simulated microgravity inhibits the proliferation and osteogenesis of rat bone marrow mesenchymal stem cells.

@article{Dai2007SimulatedMI,
  title={Simulated microgravity inhibits the proliferation and osteogenesis of rat bone marrow mesenchymal stem cells.},
  author={Zhong-quan Dai and Rui-chen Wang and Sie King Ling and Yu Wan and Yong Hui Li},
  journal={Cell proliferation},
  year={2007},
  volume={40 5},
  pages={671-84}
}
OBJECTIVES Microgravity is known to affect the differentiation of bone marrow mesenchymal stem cells (BMSCs). However, a few controversial findings have recently been reported with respect to the effects of microgravity on BMSC proliferation. Thus, we investigated the effects of simulated microgravity on rat BMSC (rBMSC) proliferation and their osteogeneic potential. MATERIALS AND METHODS rBMSCs isolated from marrow using our established effective method, based on erythrocyte lysis, were… CONTINUE READING

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