Simulated microgravity affects ciprofloxacin susceptibility and expression of acrAB-tolC genes in E. coli ATCC25922.

@article{Xu2015SimulatedMA,
  title={Simulated microgravity affects ciprofloxacin susceptibility and expression of acrAB-tolC genes in E. coli ATCC25922.},
  author={Bingxin Xu and Chenglin Li and Yanhua Zheng and Shao-yan Si and Yuhua Shi and Yuling Huang and Jianzhong Zhang and Yan Cui and Yimin Cui},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 7},
  pages={7945-52}
}
As a representative fluoroquinolone antibacterial, ciprofloxacin is frequently used to treat infections caused by bacteria such as E. coli. It is much meaningful to explore ciprofloxacin susceptibility and investigate a possible mechanism of drug susceptibility changes in E. coli ATCC25922 exposed to the environmental stress of simulated microgravity. The subculture of E. coli lasted for 7 days under simulated microgravity conditions (SMG) and normal microgravity (NG) conditions. On the 8th day… CONTINUE READING
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Changes in Gene Expression of E. coli under Conditions of Modeled Reduced Gravity

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