Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia.

@article{Andrews2014SimplifiedSS,
  title={Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia.},
  author={Ben Andrews and Levy Muchemwa and Paul Richard Kelly and Shabir Lakhi and Douglas Corbett Heimburger and Gordon R. Bernard},
  journal={Critical care medicine},
  year={2014},
  volume={42 11},
  pages={2315-24}
}
OBJECTIVE To assess the efficacy of a simple, goal-directed sepsis treatment protocol for reducing mortality in patients with severe sepsis in Zambia. DESIGN Single-center nonblinded randomized controlled trial. SETTING Emergency department, ICU, and medical wards of the national referral hospital in Lusaka, Zambia. PATIENTS One hundred twelve patients enrolled within 24 hours of admission with severe sepsis, defined as systemic inflammatory response syndrome with suspected infection and… CONTINUE READING
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