Simplified Quantification of Myocardial Flow Reserve with flurpiridaz F 18: Validation with Microspheres in a Pig Model

@article{Sherif2011SimplifiedQO,
  title={Simplified Quantification of Myocardial Flow Reserve with flurpiridaz F 18: Validation with Microspheres in a Pig Model},
  author={H. Sherif and S. Nekolla and A. Saraste and S. Reder and M. Yu and S. Robinson and M. Schwaiger},
  journal={The Journal of Nuclear Medicine},
  year={2011},
  volume={52},
  pages={617 - 624}
}
  • H. Sherif, S. Nekolla, +4 authors M. Schwaiger
  • Published 2011
  • Chemistry, Medicine
  • The Journal of Nuclear Medicine
  • The novel PET flow tracer flurpiridaz F 18 shows high myocardial extraction and slow washout. flurpiridaz F 18 PET data analysis with tracer kinetic modeling provides accurate absolute myocardial blood flow (MBF) measurements but requires in-scanner injection and complex processing. We evaluated the hypothesis that myocardial retention and standardized uptake values (SUVs) based on late uptake provide accurate estimates of myocardial flow reserve (MFR) and, thus, might allow simplified… CONTINUE READING
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    References

    SHOWING 1-10 OF 39 REFERENCES
    Interobserver and interstudy variability of myocardial blood flow and flow-reserve measurements with nitrogen 13 ammonia-labeled positron emission tomography
    • 68
    Initial Characterization of an 18F-Labeled Myocardial Perfusion Tracer
    • 129
    • PDF
    Quantification of myocardial blood flow with 82Rb dynamic PET imaging
    • 292
    Quantitative evaluation of manganese-52m as a myocardial perfusion tracer in pigs using positron emission tomography
    • 15
    Simultaneous in vitro and in vivo validation of nitrogen-13-ammonia for the assessment of regional myocardial blood flow.
    • C. Bellina, O. Parodi, +7 authors L. Donato
    • Chemistry, Medicine
    • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
    • 1990
    • 151
    Myocardial perfusion imaging with PET.
    • 62