Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death

@inproceedings{Staveness2016SimplifiedBA,
  title={Simplified Bryostatin Analogues Protect Cells from
Chikungunya Virus-Induced Cell Death},
  author={Daryl Staveness and Rana Abdelnabi and Adam J. Schrier and Brian A Loy and Vishal A. Verma and Brian A Dechristopher and Katherine E Near and Johan Neyts and Leen Delang and Pieter Leyssen and Paul A Wender},
  booktitle={Journal of natural products},
  year={2016}
}
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus showing a recent resurgence and rapid spread worldwide. While vaccines are under development, there are currently no therapies to treat this disease, except for over-the-counter (OTC) analgesics, which alleviate the devastating arthritic and arthralgic symptoms. To identify novel inhibitors of the virus, analogues of the natural product bryostatin 1, a clinical lead for the treatment of cancer, Alzheimer's disease, and HIV eradication… CONTINUE READING
1 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…