Simple nomograms to calculate sample size in diagnostic studies.

  title={Simple nomograms to calculate sample size in diagnostic studies.},
  author={Simon D Carley and S Dosman and Steven R. Jones and Mike Harrison},
  journal={Emergency medicine journal : EMJ},
  volume={22 3},
OBJECTIVES To produce an easily understood and accessible tool for use by researchers in diagnostic studies. Diagnostic studies should have sample size calculations performed, but in practice, they are performed infrequently. This may be due to a reluctance on the part of researchers to use mathematical formulae. METHODS Using a spreadsheet, we derived nomograms for calculating the number of patients required to determine the precision of a test's sensitivity or specificity. RESULTS The… CONTINUE READING
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Correspondence to: Dr Íomhar O’ Sullivan, Emergency Department, Bristol Royal Infirmary, Bristol BS2 8HW; Iomhar.O’ doi: 10.1136/emj.2003.007492

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