Simple molecule prevents mole rats from getting cancer

  title={Simple molecule prevents mole rats from getting cancer},
  author={Ewen Callaway},
Sugar matrix surrounding cells traps would-be tumours in long-lived mammal. 
Gut microbiota of animals living in polluted environments are a potential resource of anticancer molecules
It is shown that animals such as crocodiles thrive in polluted environments and are often exposed to carcinogenic agents, but still benefit from prolonged lifespan, and whether the gut microbiota of animals thriving in polluted environment possess anticancer molecules is reviewed.


High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat
It is speculated that naked mole rats have evolved a higher concentration of HA in the skin to provide skin elasticity needed for life in underground tunnels and this trait may have then been co-opted to provide cancer resistance and longevity to this species.
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat
It is proposed that the additional layer of protection conferred by two-tiered contact inhibition contributes to the remarkable tumor resistance of the naked mole-rat.
Genome sequencing reveals insights into physiology and longevity of the naked mole rat
The sequencing and analysis of the naked mole rat genome is reported, which reveals unique genome features and molecular adaptations consistent with cancer resistance, poikilothermy, hairlessness and insensitivity to low oxygen, and altered visual function, circadian rythms and taste sensing.