Simple kinetic method for assay of menadione in pharmaceuticals

  title={Simple kinetic method for assay of menadione in pharmaceuticals},
  author={Murad Helaleh},
A new simple and sensitive kinetic method for determining menadione in pure form and injection form is described, based on the reaction between menadione and sodium hydroxide to form a colored complex with a strong absorbance at 450 nm. The method is valid for determining menadione at concentrations ranging from 5.807 x 10 -1 to 7.549 x 10 -3 M. The complex forms at a 2:3 concentration ratio of menadione with respect to sodium hydroxide. The formation constant is 8.37 x 10 15 , and the molar… CONTINUE READING