Simple histone acetylation plays a complex role in the regulation of gene expression.

@article{Fukuda2006SimpleHA,
  title={Simple histone acetylation plays a complex role in the regulation of gene expression.},
  author={Hiroki Fukuda and Norihiko Sano and Shinsuke Muto and Masami Horikoshi},
  journal={Briefings in functional genomics & proteomics},
  year={2006},
  volume={5 3},
  pages={190-208}
}
Eukaryotic DNA is packaged into chromatin by histone proteins, which assemble the DNA into an organized, higher-order structure. The precise organization of chromatin is essential for faithful execution of DNA-mediated reactions such as transcription, DNA replication, DNA repair and DNA recombination. The organization of chromatin is considered to be… CONTINUE READING