Simple energy landscape model for the kinetics of functional transitions in proteins.

@article{Miyashita2005SimpleEL,
  title={Simple energy landscape model for the kinetics of functional transitions in proteins.},
  author={Osamu Miyashita and Peter G. Wolynes and Jos{\'e} N. Onuchic},
  journal={The journal of physical chemistry. B},
  year={2005},
  volume={109 5},
  pages={1959-69}
}
It is evident that protein conformational transitions play important roles in biological machinery; however, detailed pictures of these transition processes capable of making kinetic prediction are not yet available. For a full description of these transitions, we first need to describe kinematically movements between stable states. Then, more importantly… CONTINUE READING