Simple and specific high performance liquid chromatographic method for the routine monitoring of clonazepam in plasma.

Abstract

A simple, specific, and sensitive high performance liquid chromatographic (HPLC) method for the determination of clonazepam in plasma is described. The drug was extracted with chloroform at an alkaline pH using flunitrazepam as internal standard. The HPLC analysis was performed using a column packed with Spherisorb C6 reverse phase, the mobile phase being a… (More)

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Cite this paper

@article{Rovei1980SimpleAS, title={Simple and specific high performance liquid chromatographic method for the routine monitoring of clonazepam in plasma.}, author={Vincenzo Rovei and M. A. F. Sanju{\'a}n}, journal={Therapeutic drug monitoring}, year={1980}, volume={2 3}, pages={283-7} }