Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine.

@article{Smedes1982SimpleAF,
  title={Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine.},
  author={F Smedes and Joris-Jan Kraak and Hans Poppe},
  journal={Journal of chromatography},
  year={1982},
  volume={231 1},
  pages={25-39}
}
A very simple solvent extraction system for the selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine is described. The extraction system makes use of the complex formation, in alkaline medium, between diphenylborate and the diol group in the catecholamines in combination with ion-pair formation. The influence of various parameters on the distribution coefficient was investigated by analysis of the liquid phases by high-performance liquid… CONTINUE READING

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