Simple and choice reaction time performance in SIV-infected rhesus macaques.

  title={Simple and choice reaction time performance in SIV-infected rhesus macaques.},
  author={Joanne K. Marcario and Lynn A Raymond and Brian J McKiernan and Larry L Foresman and Shriya Joag and Ravi I Raghavan and Opendra Narayan and Scott Hershberger and Paul D Cheney},
  journal={AIDS research and human retroviruses},
  volume={15 6},
It is well established that HIV infection can lead to motor/cognitive disorders in humans. A number of studies have shown that simian immunodeficiency virus (SIV) infection in rhesus macaques parallels many aspects of HIV disease in humans. The purpose of this study was to define further the SIV-infected rhesus macaque as a model of neuro-AIDS. Our objective was to detect movement-related impairments in behaviorally trained, SIV-infected macaques using both simple and choice reaction time tasks… CONTINUE READING


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