Simple and accurate determination of global tau(R) in proteins using (13)C or (15)N relaxation data.

@article{Mispelter2000SimpleAA,
  title={Simple and accurate determination of global tau(R) in proteins using (13)C or (15)N relaxation data.},
  author={J Mispelter and Nadia Izadi-Pruneyre and Eric Quiniou and Elisabeth Adjadj},
  journal={Journal of magnetic resonance},
  year={2000},
  volume={143 1},
  pages={229-32}
}
In the study of protein dynamics by (13)C or (15)N relaxation measurements different models from the Lipari-Szabo formalism are used in order to determine the motion parameters. The global rotational correlation time tau(R) of the molecule must be estimated prior to the analysis. In this Communication, the authors propose a new approach in determining an accurate value for tau(R) in order to realize the best fit of R(2) for the whole sequence of the protein, regardless of the different type of… CONTINUE READING

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