Simmonds' Disease


In 1907 Paulesco demonstrated that removal of that pituitary gland caused weakness, loss of weight and death. In 1914 Simmonds reported the first case of the disease called after his name. A woman aged 38 years, after recovering from puerperal sepsis, developed amenorrhcea, increasing weakness, progressive loss of weight, anaemia, and premature senility. He… (More)