Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais

@article{Mahasirimongkol2006SimilarityOT,
  title={Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais},
  author={Surakameth Mahasirimongkol and Wasun Chantratita and Somying Promso and Ekawat Pasomsab and Natini Jinawath and Wallaya Jongjaroenprasert and Viraphong Lulitanond and Phanida Krittayapoositpot and Sissades Tongsima and Pathom Sawanpanyalert and Naoyuki Kamatani and Yusuke Nakamura and Thanyachai Sura},
  journal={Journal of Human Genetics},
  year={2006},
  volume={51},
  pages={896-904}
}
AbstractThe similarity of the marker allele frequency and linkage disequilibrium structure between two populations are major factors for the determination of the transferability and efficiency of haplotype tagging SNP derived from one population to use for an indirect association study in another population. To prove the similarity between northern East Asian populations in Hapmap and Thais, 861 SNP in 166 drug-related genes shared between Thais, Han Chinese and Japanese were analyzed for their… CONTINUE READING

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