Similarity computation strategies in the microRNA-disease network: a survey.

  title={Similarity computation strategies in the microRNA-disease network: a survey.},
  author={Quan Zou and Jinyun Liu and Li Song and Xiangxiang Zeng and Guohua Wang},
  journal={Briefings in functional genomics},
  volume={15 1},
Various microRNAs have been demonstrated to play roles in a number of human diseases. Several microRNA-disease network reconstruction methods have been used to describe the association from a systems biology perspective. The key problem for the network is the similarity computation model. In this article, we reviewed the main similarity computation methods and discussed these methods and future works. This survey may prompt and guide systems biology and bioinformatics researchers to build more… CONTINUE READING
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