Similarity-based modeling in large-scale prediction of drug-drug interactions


Drug-drug interactions (DDIs) are a major cause of adverse drug effects and a public health concern, as they increase hospital care expenses and reduce patients' quality of life. DDI detection is, therefore, an important objective in patient safety, one whose pursuit affects drug development and pharmacovigilance. In this article, we describe a protocol… (More)
DOI: 10.1038/nprot.2014.151


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@article{Vilar2014SimilaritybasedMI, title={Similarity-based modeling in large-scale prediction of drug-drug interactions}, author={Santiago Vilar and Eugenio Uriarte and Lourdes Santana and Tal Lorberbaum and George Hripcsak and Carol Friedman and Nicholas P. Tatonetti}, journal={Nature Protocols}, year={2014}, volume={9}, pages={2147-2163} }