Similarity Between Obesity and Drug Addiction as Assessed by Neurofunctional Imaging

  title={Similarity Between Obesity and Drug Addiction as Assessed by Neurofunctional Imaging},
  author={G. Wang and N. Volkow and P. Thanos and J. Fowler},
  journal={Journal of Addictive Diseases},
  pages={39 - 53}
  • G. Wang, N. Volkow, +1 author J. Fowler
  • Published 2004
  • Medicine
  • Journal of Addictive Diseases
  • SUMMARY Overeating in obese individuals shares similarities with the loss of control and compulsive drug taking behavior observed in drug-addicted subjects. The mechanism of these behaviors is not well understood. Our prior studies with positron emission tomography (PET) in drug-addicted subjects documented reductions in striatal dopamine (DA) D2 receptors. In pathologically obese subjects, we found reductions in striatal DA D2 receptors similar to that in drug-addicted subjects. Moreover, DA… CONTINUE READING
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