Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.

@article{Zhong2014SimilaritiesOB,
  title={Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.},
  author={Shuming Zhong and Ying Wang and Guoxiang Zhao and Qi Xiang and Xueying Ling and Sirun Liu and Li Huang and Yanbin Jia},
  journal={Journal of affective disorders},
  year={2014},
  volume={168},
  pages={380-6}
}
BACKGROUND Depression in the context of bipolar disorder (BD) is often misdiagnosed as major depressive disorder (MDD), leading to mistreatments and poor clinical outcomes for many bipolar patients. Previous neuroimaging studies found mixed results on brain structure, and biochemical metabolism of the two disorders. To eliminate the compounding effects of medication, and aging, this study sought to investigate the brain biochemical changes of treatment-naïve, non-late-life patients with MDD and… CONTINUE READING

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