Similarities in the induction of post-Golgi vesicles by the vaccinia virus F13L protein and phospholipase D.

@article{Husain2002SimilaritiesIT,
  title={Similarities in the induction of post-Golgi vesicles by the vaccinia virus F13L protein and phospholipase D.},
  author={Matloob Husain and Bernard Moss},
  journal={Journal of virology},
  year={2002},
  volume={76 15},
  pages={7777-89}
}
Intracellular mature vaccinia virions are wrapped by cisternae, derived from virus-modified trans-Golgi or endosomal membranes, and then transported via microtubules to the cell periphery. Two viral proteins, encoded by the F13L and B5R open reading frames, are essential for the membrane-wrapping step. Previous transfection studies indicated that F13L induces the formation of post-Golgi vesicles that incorporate the B5R protein and that this activity depends on an intact F13L phospholipase… CONTINUE READING

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