Similar withdrawal severity in adolescents and adults in a rat model of alcohol dependence.

@article{Morris2010SimilarWS,
  title={Similar withdrawal severity in adolescents and adults in a rat model of alcohol dependence.},
  author={Stephanie A. Morris and Matthew L. Kelso and Daniel J Liput and Sarah A Marshall and Kimberly Nixon},
  journal={Alcohol},
  year={2010},
  volume={44 1},
  pages={89-98}
}
Alcohol use during adolescence leads to increased risk of developing an alcohol use disorder (AUD) during adulthood. Converging evidence suggests that this period of enhanced vulnerability for developing an AUD may be due to the adolescent's unique sensitivity and response to alcohol. Adolescent rats have been shown to be less sensitive to alcohol intoxication and withdrawal susceptibility; however, age differences in ethanol pharmacokinetics may underlie these effects. Therefore, this study… CONTINUE READING

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