Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically.

@article{Aitken1998SimilarPO,
  title={Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically.},
  author={Peter G. Aitken and Geoffrey C. Tombaugh and Dennis A. Turner and G. G. Somjen},
  journal={Journal of neurophysiology},
  year={1998},
  volume={80 3},
  pages={1514-21}
}
Neuron membrane changes and ion redistribution during normoxic spreading depression (SD) induced, for example, by potassium injection, closely resemble those that occur during hypoxic SD-like depolarization (HSD) induced by oxygen withdrawal, but the degree to which the two phenomena are related is controversial. We used extracellular electrical recording and imaging of intrinsic optical signals in hippocampal tissue slices to compare 1) initiation and spread of these two phenomena and 2) the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 45 extracted citations

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2017
View 1 Excerpt

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2017

References

Publications referenced by this paper.
Showing 1-10 of 16 references

to slowly rise during the hyperpolarizing phase in hypoxia, GRAFSTEIN, B. Mechanism of spreading cortical depression. J. Neurophyswhereas it stays constant during normoxic SD until the sud- iol

A J.
Latinoam • 1974
View 1 Excerpt
Highly Influenced

Spreading depressioneffect on gap junctions, we do not believe this to be the like hypoxic depolarization in CA1 and fascia dentata of hippocampal

P. G. AITKEN, G. G. SOMJEN
Soc. Neurosci. Abstr • 1997

Electrophysiological and slices reveals selective regional vulnerability to anoxic depolarization optical changes in slices of rat hippocampus during spreading depression, and swelling

N. R. KREISMAN, J. E. TORRES, GOZAL, C. P. TAYLOR, F. E. DUDEK
Soc. Neurosci. Abstr • 1996
View 1 Excerpt

The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 1992

Selective vulnerability in the gerbil hippocampus pression and global cerebral ischemia of rats

T. KIRINO, K. SANO
Acta Neuropathol • 1984
View 1 Excerpt

Cellular Approaches to the Treatment of Neurological Disease

I. S. edKASS, P. LIPTON
Extracelrosci. Abstr • 1983

Similar Papers

Loading similar papers…