Similar inflammatory response in human whole blood to live Streptococcus pneumoniae of different serotypes.

@article{Kragsbjerg2004SimilarIR,
  title={Similar inflammatory response in human whole blood to live Streptococcus pneumoniae of different serotypes.},
  author={Peter Kragsbjerg and Margaretha Jurstrand and Hans Fredlund},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2004},
  volume={10 2},
  pages={
          174-7
        }
}
Differences in inflammatory responses in human adult whole blood to live pneumococcal serotypes 3, 7F, 9V and 23F were investigated. Using flow cytometry and ELISA, oxidative burst, expression of activation markers CD11b/CD18, and in-vitro production of tumour necrosis factor-alpha, interleukin-6 (IL-6) and interleukin-8 were measured. There was no significant difference between the serotypes regarding any of the variables investigated, although there was a trend towards higher concentrations… CONTINUE READING
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