Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals

  title={Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals},
  author={Reuben M. Buckley and R. Daniel Kortschak and Joy M. Raison and David L. Adelson},
  journal={Genome Biology and Evolution},
  pages={2336 - 2353}
The factors guiding retrotransposon insertion site preference are not well understood. Different types of retrotransposons share common replication machinery and yet occupy distinct genomic domains. Autonomous long interspersed elements accumulate in gene-poor domains and their non-autonomous short interspersed elements accumulate in gene-rich domains. To determine genomic factors that contribute to this discrepancy we analysed the distribution of retrotransposons within the framework of… 

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