Simian virus 40 agnoprotein facilitates perinuclear-nuclear localization of VP1, the major capsid protein.

@article{Carswell1986SimianV4,
  title={Simian virus 40 agnoprotein facilitates perinuclear-nuclear localization of VP1, the major capsid protein.},
  author={Susan Carswell and James C. Alwine},
  journal={Journal of virology},
  year={1986},
  volume={60 3},
  pages={1055-61}
}
The agnoprotein of simian virus 40 (SV40) is a 61-amino-acid protein encoded in the leader of some late mRNAs. In indirect immunofluorescence studies with antisera against SV40 capsid proteins, we show that mutants which make no agnoprotein display abnormal perinuclear-nuclear localization of VP1, the major capsid protein, but not VP2 or VP3, the minor capsid proteins. In wild-type (WT) SV40-infected CV-1P cells, VP1 was found predominantly in the cytoplasm until 36 h postinfection (p.i… CONTINUE READING