Simian immunodeficiency virus inhibits bone marrow hematopoietic progenitor cell growth.

@article{Watanabe1990SimianIV,
  title={Simian immunodeficiency virus inhibits bone marrow hematopoietic progenitor cell growth.},
  author={Minoru Watanabe and Douglas J. Ringler and Masataka Nakamura and Peter A Delong and Norman L. Letvin},
  journal={Journal of virology},
  year={1990},
  volume={64 2},
  pages={656-63}
}
The pathogenic mechanisms underlying the depressed hematopoietic functions seen in human immunodeficiency virus-infected individuals were explored in rhesus monkeys infected with the simian immunodeficiency virus of macaques (SIVmac). Bone marrow hematopoietic progenitor cell colony formation, both granulocyte/macrophage (CFU-GM) and erythrocyte (BFU-E), was shown to be decreased in number in SIVmac-infected rhesus monkeys. SIVmac was readily isolated from bone marrow cells of infected monkeys… CONTINUE READING

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