Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.

@article{Pandrea2006SimianIV,
  title={Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.},
  author={Ivona V. Pandrea and Cristian Apetrei and Jason Dufour and Nora Dillon and Joseph Barbercheck and Michael G. Metzger and B{\'e}atrice Jacquelin and Rudolf P. Bohm and Preston A Marx and Bernard Krust and Vanessa M Hirsch and Michaela M{\"u}ller-Trutwin and Andrew A Lackner and Ronald S Veazey},
  journal={Journal of virology},
  year={2006},
  volume={80 10},
  pages={
          4858-67
        }
}
Caribbean-born African green monkeys (AGMs) were classified as Chlorocebus sabaeus by cytochrome b sequencing. Guided by these phylogenetic analyses, we developed a new model for the study of simian immunodeficiency virus (SIV) infection in natural hosts by inoculating Caribbean AGMs with their species-specific SIVagm.sab. SIVagm.sab replicated efficiently in Caribbean AGM peripheral blood mononuclear cells in vitro. During SIVagm.sab primary infection of six Caribbean AGMs, the virus… CONTINUE READING
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