Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains.

@article{Tsarev1991SimianHA,
  title={Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains.},
  author={S. Tsarev and S. Emerson and M. Balayan and J. Ticehurst and R. Purcell},
  journal={The Journal of general virology},
  year={1991},
  volume={72 ( Pt 7)},
  pages={
          1677-83
        }
}
Fragments of cDNA representing greater than 99% of the entire genome of wild-type hepatitis A virus (HAV) strain AGM-27, isolated from an African green monkey, were obtained by the polymerase chain reaction and sequenced. Comparison with other HAV isolates revealed differences in the predicted amino acid sequence in functionally critical parts of the genome. Comparison of the biological properties of AGM-27 with those of human wild-type and cell culture-adapted HM-175 strains revealed that AGM… Expand
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