SimLoRD: Simulation of Long Read Data

@article{Stcker2016SimLoRDSO,
  title={SimLoRD: Simulation of Long Read Data},
  author={Bianca K. St{\"o}cker and Johannes K{\"o}ster and Sven Rahmann},
  journal={Bioinformatics},
  year={2016},
  volume={32 17},
  pages={2704-6}
}
MOTIVATION Third generation sequencing methods provide longer reads than second generation methods and have distinct error characteristics. While there exist many read simulators for second generation data, there is a very limited choice for third generation data. RESULTS We analyzed public data from Pacific Biosciences (PacBio) SMRT sequencing, developed an error model and implemented it in a new read simulator called SimLoRD. It offers options to choose the read length distribution and to… CONTINUE READING

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