Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases.

Abstract

Silymarin, a complex flavonolignan from the 'milk thistle' (Silybum marianum) plant, exhibits anticarcinogenic, anti-inflammatory and cytoprotective effects. Several reports have demonstrated immunosuppressive activity of silymarin; however, the molecular mechanisms involved in immunomodulatory activities of silymarin are not fully understood yet. In this… (More)
DOI: 10.1111/bcpt.12032

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Cite this paper

@article{Gharagozloo2013SilymarinIC, title={Silymarin inhibits cell cycle progression and mTOR activity in activated human T cells: therapeutic implications for autoimmune diseases.}, author={Marjan Gharagozloo and Elahe N Javid and Abbas Rezaei and Kazem Mousavizadeh}, journal={Basic & clinical pharmacology & toxicology}, year={2013}, volume={112 4}, pages={251-6} }