Silymarin in the prevention and treatment of liver diseases and primary liver cancer.

@article{Fher2012SilymarinIT,
  title={Silymarin in the prevention and treatment of liver diseases and primary liver cancer.},
  author={J{\'a}nos F{\'e}her and Gabriella Lengyel},
  journal={Current pharmaceutical biotechnology},
  year={2012},
  volume={13 1},
  pages={210-7}
}
In chronic liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver diseases, drug- and chemical-induced hepatic toxicity), the antioxidant medicines such as silymarin can have beneficial effect. Liver cirrhosis, non-alcoholic fatty liver and steatohepatitis are risk factors for hepatocellular carcinoma (HCC). Insulin resistance and oxidative stress are the major pathogenetic mechanisms leading the hepatic cell injury in these patients. The silymarin exerts membrane… CONTINUE READING