Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells

Abstract

Hepatocellular carcinoma (HCC) is a global health burden that is associated with limited treatment options and poor patient prognoses. Silybin (SIL), an antioxidant derived from the milk thistle plant (Silybum marianum), has been reported to exert hepatoprotective and antitumorigenic effects both in vitro and in vivo. While SIL has been shown to have potent… (More)
DOI: 10.1371/journal.pone.0083699

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@inproceedings{Zhang2013SilybinMediatedIO, title={Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells}, author={Song Zhang and Yang Yang and Zhenxing Liang and Weixun Duan and Jian Yang and Juanjuan Yan and Ning Wang and Wenqiang Feng and Meiling Ding and Yongzhan Nie and Zhenxiao Jin}, booktitle={PloS one}, year={2013} }