Silver products for medical indications: risk-benefit assessment.

@article{Fung1996SilverPF,
  title={Silver products for medical indications: risk-benefit assessment.},
  author={M C Fung and D. L. Bowen},
  journal={Journal of toxicology. Clinical toxicology},
  year={1996},
  volume={34 1},
  pages={
          119-26
        }
}
  • M. Fung, D. Bowen
  • Published 1996
  • Medicine
  • Journal of toxicology. Clinical toxicology
BACKGROUND Legitimate medicinal use of silver-containing products has dramatically diminished over the last several decades. Recently, however, some manufacturers have begun to enthusiastically promote oral colloidal silver proteins as mineral supplements and for prevention and treatment of many diseases. Indiscriminate use of silver products can lead to toxicity such as argyria. OBJECTIVE To assist health care professionals in a risk versus benefit assessment of over-the-counter silver… 
Medical Uses of Silver: History, Myths, and Scientific Evidence.
TLDR
The journey of silver in medicine going from the alternative or do-it-yourself drug to scientific evidence related to its uses is dealt with.
Argyria following the use of dietary supplements containing colloidal silver protein.
TLDR
This case report highlights the potential for toxicity following the use of dietary supplements and demonstrates the importance of physician inquiry regarding alternative medicines, as well as reviewing the past and present medicinal roles of silver.
In vitro intestinal toxicity of commercially available spray disinfectant products advertised to contain colloidal silver.
TLDR
The cytotoxicity for each of the colloidal silver products was attributed to the particulate silver, soluble silver or non‑silver matrix constituents.
Exposure-related health effects of silver and silver compounds: a review.
A critical review of studies examining exposures to the various forms of silver was conducted to determine if some silver species are more toxic than others. The impetus behind conducting this review
High silver concentrations in biological samples following different exposures: Two case reports.
  • B. Lelièvre, A. Tellier, +5 authors M. Deguigne
  • Medicine
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements
  • 2021
TLDR
The silver concentrations were elevated compared to population reference values and confirmed the hypotheses for the patients: the significant consumption of sweets coated with silver nanoparticles and the topical application of a cream containing silver to burns over a large area.
Silver nasal sprays: Misleading Internet marketing
TLDR
It is concluded that information about silver-containing nasal sprays on the Internet is misleading and inaccurate and otolaryngologists should be aware of the misinformation their patients may be receiving about these products.
An historical overview of the use of silver in wound management
TLDR
There is now a rationale for the judicious use of suitable topical antisepsis in certain colonized, critically Colonized, and infected wounds.
Silver and Gold
TLDR
The present chapter discusses properties, production, uses, exposure assessment, toxic effects, and several clinical cases of these transitional metals.
SILVER, MILD SILVER PROTEIN
One of the most effective anti-microbial therapies available to wholistic health practitioners today is Mild Silver Protein (MSP). Silver use as an antibiotic is not new. It has a long history and it
A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices
  • A. Lansdown
  • Medicine
    Advances in pharmacological sciences
  • 2010
TLDR
The mechanisms of absorption and metabolism of silver in the human body, presumed mechanisms of argyria and argyrosis, and the elimination of silver-protein complexes in the bile and urine are discussed.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 39 REFERENCES
Argyria: clinical implications of exposure to silver nitrate and silver oxide.
  • K. Rosenman, A. Moss, S. Kon
  • Chemistry, Medicine
    Journal of occupational medicine. : official publication of the Industrial Medical Association
  • 1979
TLDR
The results of this examination generally support the benign nature of argyria, although the question of silver causing a decrement in kidney function and night vision is not settled.
Silver retention, total body silver and tissue silver concentrations in argyria associated with exposure to an anti‐smoking remedy containing silver acetate
TLDR
It is indicated that the uptake of silver may be substantial following the use of oral silver preparations after the excessive use of an oral anti‐smoking remedy containing silver acetate.
Systemic argyria secondary to topical silver nitrate.
TLDR
Although the systemic distribution of silver in both elemental and ionic forms can be linked with no systemic toxicity, the resultant pigmentation can be devastating to the patient.
CLINICAL SPECTROSCOPY: SEVENTY CASES OF GENERALIZED ARGYROSIS FOLLOWING ORGANIC AND COLLOIDAL SILVER MEDICATION, INCLUDING A BIOSPECTROMETRIC ANALYSIS OF TEN CASES
TLDR
Within the past year, following intranasal applications with Argyrol and Neo-Silvol in fifteen children under 10 years of age, an argyrosis developed, and ten of these fifteen children were girls.
Handbook on the toxicology of metals
"Handbook of the Toxicology of Metals" is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a
Cytotoxicity to human leukocytes by topical antimicrobial agents used for burn care.
We tested two topical antimicrobial agents (TAAs), silver sulfadiazine and mafenide acetate, to determine their cytotoxic effects when human lymphocytes and neutrophils were incubated with the agents
[Generalized argyrosis].
TLDR
After acute coronary failure with marked nicotine abuse autopsy revealed granulated deposits of silver in the corium, particularly on elastic fibres, at the sweat glands, sebaceous glands and hair follicles, as well as in the portal fields.
Bone marrow toxicity by silver sulfadiazine.
TLDR
In vitro SSD is directly cytotoxic to myelopoietic tissue, and in vivo, alters the myeloid cell compartment, and may explain the transient leukopenia frequently observed in patients receiving topical chemoprophylaxis with SSD.
[Argyrosis of the urinary tract after silver nitrate instillation: report of a case].
TLDR
It is concluded that this patient developed argyrosis of the urinary tract, and previously published papers concerning complications of silver nitrate instillation are reviewed.
An experimental study on silver in the nervous system and on aspects of its general cellular toxicity.
  • J. Rungby
  • Medicine
    Danish medical bulletin
  • 1990
TLDR
The consequences of silver in the nervous system were evaluated by volumetric measurements on developing rat hippocampi which showed that silver induced a decrease in the total volume of hippocampal pyramidal cells.
...
1
2
3
4
...