Silver nanoparticles synthesized from Adenium obesum leaf extract induced DNA damage, apoptosis and autophagy via generation of reactive oxygen species.

@article{Farah2016SilverNS,
  title={Silver nanoparticles synthesized from Adenium obesum leaf extract induced DNA damage, apoptosis and autophagy via generation of reactive oxygen species.},
  author={Mohammad Abul Farah and Mohammad Ajmal Ali and Shen-Ming Chen and Ying Li and Fahad Mohammad Al-Hemaid and Faisal Mohammad Abou-Tarboush and Khalid Mashay Al-Anazi and Joongku Lee},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2016},
  volume={141},
  pages={158-169}
}
Silver nanoparticles (AgNPs) are an important class of nanomaterial used for a wide range of industrial and biomedical applications. Adenium obesum is a plant of the family Apocynaceae that is rich in toxic cardiac glycosides; however, there is scarce information on the anticancer potential of its AgNPs. We herein report the novel biosynthesis of AgNPs using aqueous leaf extract of A. obesum (AOAgNPs). The synthesis of AOAgNPs was monitored by color change and ultraviolet-visible spectroscopy… CONTINUE READING
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