• Medicine, Chemistry
  • Published in
    Physical chemistry chemical…
    2009
  • DOI:10.1039/b904744a

Silver nanoparticles self assembly as SERS substrates with near single molecule detection limit.

@article{Fan2009SilverNS,
  title={Silver nanoparticles self assembly as SERS substrates with near single molecule detection limit.},
  author={Meikun Fan and Alexandre G Brolo},
  journal={Physical chemistry chemical physics : PCCP},
  year={2009},
  volume={11 34},
  pages={
          7381-9
        }
}
Highly sensitive SERS substrates with a limit of detection in the zeptomole (for Nile blue A and oxazine 720) range were fabricated through a bottom-up strategy. Ag nanoparticles (Ag NPs) were self-assembled onto glass slides by using 3-mercaptopropyltrimethoxysilane (MPTMS) sol-gel as linker. The substrates were characterized by UV-Vis and AFM after each deposition of Ag NPs. It was found that the glass slide presented just a few Ag NPs aggregates scattered throughout the surface after just… CONTINUE READING

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