Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells.

@article{Wang2013SilverNI,
  title={Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells.},
  author={Zhe Wang and Sijin Liu and Juan Ma and Guangbo Qu and Xiaoyan Wang and Su-ping Yu and Jiuyang He and Jingfu Liu and Tian Xia and Guibin Jiang},
  journal={ACS nano},
  year={2013},
  volume={7 5},
  pages={
          4171-86
        }
}
Due to its antimicrobial activity, nanosilver (nAg) has become the most widely used nanomaterial. Thus far, the mechanisms responsible for nAg-induced antimicrobial properties and nAg-mediated toxicity to organisms have not been clearly recognized. Silver (Ag) ions certainly play a crucial role, and the form of nanoparticles can change the dissolution rate, bioavailability, biodistribution, and cellular uptake of Ag. However, whether nAg exerts direct "particle-specific" effects has been under… Expand
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