Silver Diamine Fluoride: A Caries “Silver-Fluoride Bullet”

@article{Rosenblatt2009SilverDF,
  title={Silver Diamine Fluoride: A Caries “Silver-Fluoride Bullet”},
  author={Aronita Rosenblatt and T{\^a}ania L{\'u}cia Montenegro Stamford and Richard Niederman},
  journal={Journal of Dental Research},
  year={2009},
  volume={88},
  pages={116 - 125}
}
The antimicrobial use of silver compounds pivots on the 100-year-old application of silver nitrate, silver foil, and silver sutures for the prevention and treatment of ocular, surgical, and dental infections. [] Key Method A five-database search, reference review, and hand search identified 99 human clinical trials in three languages published between 1966 and 2006. Dual review for controlled clinical trials with the patient as the unit of observation, and excluding cross-sectional, animal, in vitro studies…

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Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentin Caries in Chinese Pre-school Children
TLDR
Silver diamine fluoride was found to be effective in arresting dentin caries in primary anterior teeth in pre-school children.
Fluoride varnishes for preventing dental caries in children and adolescents.
TLDR
A substantial caries-inhibiting effect of fluoride varnish in both the permanent and the deciduous dentitions is suggested based largely on trials with no treatment controls, and a funnel plot of the seven studies indicated no relationship between prevented fraction and study precision.
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The benefits of topical fluorides have been firmly established on a sizeable body of evidence from randomized controlled trials, and the formal examination of sources of heterogeneity between studies has been important in the overall conclusions reached.
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TLDR
Topical fluorides used in addition to fluoride toothpaste achieve a modest reduction in caries compared to toothpaste used alone.
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TLDR
Fluoride toothpastes in comparison to mouthrinses or gels appear to have a similar degree of effectiveness for the prevention of dental caries in children.
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TLDR
Whether or not treatment of carious dentine with silver fluoride represents a biologically acceptable clinical procedure cannot be answered on the basis of pulpal histology alone, and the very high concentration of fluoride in commercial preparations of silver fluoride raises several questions concerning its clinical safety.
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