Silver, titanium dioxide, and zinc oxide nanoparticles trigger miRNA/isomiR expression changes in THP-1 cells that are proportional to their health hazard potential

@article{Ndika2019SilverTD,
  title={Silver, titanium dioxide, and zinc oxide nanoparticles trigger miRNA/isomiR expression changes in THP-1 cells that are proportional to their health hazard potential},
  author={Joseph Ndika and Umair Seemab and Wing-Lam Poon and Vittorio Fortino and Hani El‐Nezami and Piia Karisola and Harri Alenius},
  journal={Nanotoxicology},
  year={2019},
  volume={13},
  pages={1380 - 1395}
}
Abstract After over a decade of nanosafety research, it is indisputable that the vast majority of nano-sized particles induce a plethora of adverse cellular responses – the severity of which is linked to the material’s physicochemical properties. Differentiated THP-1 cells were previously exposed for 6 h and 24 h to silver, titanium dioxide, and zinc oxide nanoparticles at the maximum molar concentration at which no more than 15% cellular cytotoxicity was observed. All three nanoparticles… 
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