Silver(I)-imidazole cyclophane gem-diol complexes encapsulated by electrospun tecophilic nanofibers: formation of nanosilver particles and antimicrobial activity.

@article{Melaiye2005SilverIimidazoleCG,
  title={Silver(I)-imidazole cyclophane gem-diol complexes encapsulated by electrospun tecophilic nanofibers: formation of nanosilver particles and antimicrobial activity.},
  author={Abdulkareem Melaiye and Zhaohui Sun and Khadijah M. Hindi and Amy Milsted and Daniel Ely and Darrell H. Reneker and Claire A. Tessier and Wiley J. Youngs},
  journal={Journal of the American Chemical Society},
  year={2005},
  volume={127 7},
  pages={
          2285-91
        }
}
Silver(I)-imidazole cyclophane gem-diol complex, 3 [Ag2C36 N10(O)4](2+)2(x)-, where x = OH- or CO3(2-), was synthesized and well characterized. The minimum inhibition concentration tests showed that the aqueous form of 3 is 2 times less effective as an antibiotic than 0.5% AgNO3, with about the same amount of silver. The antimicrobial activity of 3 was enhanced when encapsulated into Tecophilic polymer by electrospinning to obtain mats made of nano-fibers. The fiber mats released nanosilver… CONTINUE READING

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