Silkworm and spider silk scaffolds for chondrocyte support

  title={Silkworm and spider silk scaffolds for chondrocyte support},
  author={K. Gellynck and P. Verdonk and E. Nimmen and K. Almqvist and T. Gheysens and G. Schoukens and L. Langenhove and P. Kiekens and J. Mertens and G. Verbruggen},
  journal={Journal of Materials Science: Materials in Medicine},
  • K. Gellynck, P. Verdonk, +7 authors G. Verbruggen
  • Published 2008
  • Materials Science, Medicine
  • Journal of Materials Science: Materials in Medicine
  • Objective To create scaffolds with silkworm cocoon, spider egg sac and spider dragline silk fibres and examine their use for chondrocyte attachment and support. Methods Three different kinds of scaffolds were developed with Bombyx mori cocoon, Araneus diadematus egg sac and dragline silk fibres. The attachment of human articular cartilage cells were investigated on these bioprotein matrices. The chondrocytes produced an extracellular matrix which was studied by immunostaining. Moreover, the… CONTINUE READING
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