Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology

@article{Lippert2009SiliconAO,
  title={Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology},
  author={W. Peter Lippert and Christian Burschka and Kathrin H G{\"o}tz and Martin Kaupp and Diana G. Ivanova and Claudine Gaudon and Yoshiteru Sato and Pierre Antony and Natacha Rochel and Dino Moras and Hinrich Gronemeyer and Reinhold Tacke},
  journal={ChemMedChem},
  year={2009},
  volume={4}
}
C/Si switch: Twofold sila‐substitution (C/Si exchange) in the RXR‐selective retinoids 4 a (SR11237) and 5 a leads to 4 b (disila‐SR11237) and 5 b, respectively. Chemistry and biology of the C/Si pairs are reported. 
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