Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.

@article{Yamashita2011SilicaAT,
  title={Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.},
  author={Kunihiko Yamashita and Yasuo Yoshioka and Kazuma Higashisaka and Kazuya Mimura and Yuki Morishita and Masatoshi Nozaki and Tokuyuki Yoshida and Toshinobu Ogura and Hiromi Nabeshi and Kazuya Nagano and Y Abe and Haruhiko Kamada and Youko Monobe and Takayoshi Imazawa and Hisae Aoshima and Kiyoshi Shishido and Yuichi Kawai and Tadanori Mayumi and Shin-ichi Tsunoda and Norio Itoh and Tomoaki Yoshikawa and Itaru Yanagihara and Shigeru Saito and Yasuo Tsutsumi},
  journal={Nature nanotechnology},
  year={2011},
  volume={6 5},
  pages={
          321-8
        }
}
The increasing use of nanomaterials has raised concerns about their potential risks to human health. Recent studies have shown that nanoparticles can cross the placenta barrier in pregnant mice and cause neurotoxicity in their offspring, but a more detailed understanding of the effects of nanoparticles on pregnant animals remains elusive. Here, we show that silica and titanium dioxide nanoparticles with diameters of 70 nm and 35 nm, respectively, can cause pregnancy complications when injected… CONTINUE READING
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